The Great Lakes Region of the Construction Specifications Institute includes the states of Indiana, Kentucky, Michigan, Ohio, and West Virginia. CSI members that have their primary address in these states are members of the Great Lakes Region.

There are 15 CSI chapters in the Great Lakes Region including Akron-Canton, Bluegrass, Cincinnati, Cleveland, Columbus, Dayton-Miami Valley, Evansville, Fort Wayne, Grand Rapids, Indianapolis, Lansing, Louisville, Metropolitan Detroit, Saginaw Valley, and Toledo.

Activities and opportunities for engagement with the Great Lakes Region are open to all members of the region, regardless of chapter affiliation.

The Great Lakes Region is incorporated as a a not-for-profit organization in the state of Ohio.